Seitz® K–Series Depth Filter Sheets

With 13 different retention rates the K-series represents the standard depth filter sheet series of Pall SeitzSchenk Filtersystems. These sheets consist of a cellulose matrix which contains very fine kieselguhr mixtures and perlite as filtration-active substances.

The SEITZ-EKS, the SEITZ-EK 1 and the SEITZ-EK are used for sterilising filtration duties, whereas the SEITZ-KS 50 and SEITZKS 80 are classified as micro-organism-reducing depth filters. They can produce a sterile filtrate at low organism counts in the unfiltered product. K 100 through to K 900 cover the entire range from fine filtration via clarifying filtration to coarse filtration.

Successful bioburden reduction to achieve very low organism counts necessitates knowledge of the microbiological status of the product. The filtration procedure has to be adapted in such a way that the organism challenge limit validated for a particular depth filter sheet is not exceeded. Differential pressure must be limited to a maximum of 1.5 bar (14.5 psi)
The flow velocity should not exceed 500 L/m² /h. These figures may be lower in the case of difficult or demanding products.

To obtain assurace of sterile filtrate through a sterilizing membrane filter cartridge, downstream of depth filter sheets is essential. ,br>

Typical LRV Figures (Log Reduction Value)

EKS	> 8.5(1)
EK 1	> 7.5(1)
EK	>7.0(2)
KS 50	>6.5(2)
KS 80	> 6.0(2)

¹ Test organisms: Brevundimonas diminuta.
² Test organisms: Serratia marcescens.

 

Technical Data
Sheet	Weight per Area [g/m2]	Thickness [mm]	Ash Content[%]	Extractable Ions Soluble in 0.025 µm H2SO4 [mg/m2]
				Ca	Fe	Al
FE
EKS	1400	3.7	58	1800	15	150
EK1	1400	3.7	51	1600	15	140
EK	1350	3.7	46	1400	10	120
KS50	1350	3.7	46	1400	10	120
KS80	1350	3.7	46	1200	15	120
K100	1350	3.7	46	1400	15	120
K150	1350	3.9	46	1300	15	120
K200	1350	3.9	46	1200	15	110
K250	1300	4.0	46	1000	15	70
K300	1300	4.2	46	900	15	50
K700	1300	4.1	46	900	15	50
K800	1300	4.1	46	900	15	45
K900	1300	4.3	46	900	25	40
Heavy metals < 50 ppm (according to the Recommendation XXXVI/1 BgVV-German Federal Institute for Health Protection of Consumers and Veterinary Medicine).

 

The following Certificates are available:

• Certificate of Compliance according to DIN 50049-2.1/EN 10204-2.1
• Materials Safety Data Sheet

The depth filters conform to the Recommendation XXXVI/1 BgVV (German Federal Institute for Health Protection of Consumers and Veterinary Medicine) and meet the requirements of the Lebensmittelund edarfsgegenständegesetz – LMBG – (Foodstuff and other Commodities Act), in particular §§ 5, 30 and 31.

Sheet

EKS	Vaccines, pharmaceuticals and BioPharmaceuticals, phytopharmaceuticals (sterile filtration), plasma fractionation, serum, aqueous cosmetics (clarifying and fine filtration)
EK1	Aqueous cosmetics (clarifying and fine filtration), pharmaceuticals and BioPharmaceuticals, plasma fractionation
EK	Pharmaceuticals and BioPharmaceuticals.
KS50	Phytopharmaceuticals (clarifying filtration)
KS80	Antibiotics (clarifying filtration), vaccines, infusion solutions, plant extracts (clarifying filtration), plasma fractionation
K100	Pharmaceuticals and BioPharmaceuticals (clarifying filtration), serum (pre-filtration)
K200 K250	Vaccines (prefiltration), phytopharmaceuticals (clarifying filtration)
K300	Antibiotics (clarifying filtration), cosmetics (clarifying filtration)
K700	Antibiotics (clarifying filtration), serum (prefiltration), cell harvest
K800	Vaccines (prefiltration), cell harvest
K900	Infusion solutions (prefiltration), cosmetics (particle filtration), cell harvest

Please contact your Pall representative.