Cascada™ BIO-Water Systems: Compliance With BS3978/ISO 3696 Specification for Water for Laboratory Use, Grade 1

The Cascada BIO-water System is fed with partially purified water. It produces extremely high ultrapure water for life science applications, suitable for all molecular, pharmaceutical, and microbiological applications.

The product water conforms to BS3978/ISO 3696 Grade 1 specification.

Parameter	Grade 1 Specification	Typical Measured Values
Resistivity (Mohm-cm at 25 °C)	> 10	18.2
Silica (ppb)	< 500	< 1
Absorbance at 254 nm	< 0.001/cm	< 0.001/cm

A Cascada BIO-water System was fed with water from a Cascada RO-water System with a conductivity of 42 µS/cm and a TOC of 50 ppb C. The unit was operated intermittently and product water dispensed to simulate typical use patterns.

Resistivity was logged online using a Thornton 200CR meter. Samples were taken for silica analysis and absorbance measurements at various times.

Samples were analyzed for silica by ICP-MS using a PlasmaQuad 3.

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