Ion Exchange Chromatography Membranes

Ion Exchange Membranes Introduction

In many areas, chromatography resins are the media of choice for chromatography applications. In some instances, where resin-based methods have limitations (e.g., purification of viruses or large molecules), membranes have proven to be a robust, scalable, and economical alternative to resins. Chromatography membranes offer faster flow rates as compared to their resin counterparts.  

For ion exchange applications (see Table 4.1), Pall offers Mustang ion exchange membrane. This technology is available in several formats including a syringe filter column and a 96-well filter plate. 

Table 4.1

Ion Exchange Applications

Type of Ion Exchanger	Common Abbreviation	Functional Group	Product Name	Description
Strong Anion	Q	Quarternary Ammonium	Acrodisc® Unit with Mustang Q AcroPrep™ Filter Plate with Mustang Q	Syringe filter column 96-well filter plate(350 μL or 1 mL)
Strong Cation	S	Sulfonic Acid	Acrodisc® Unit with Mustang S AcroPrep™ Filter Plate with Mustang S	Syringe filter column 96-well filter plate (350 μL or 1 mL)