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Asymmetric Membrane
For Highly Efficient Sample Clarification
Asymmetric membranes provide fast flow, low pressure drops, and highly consistent flow rates in applications such as prefiltration and clarification. Asymmetric membranes are different from conventionally cast microporous membranes in that the larger pores on the upstream side of the membrane act as a prefilter while the absolute rated downstream side, or exclusion zone, act as an absolute cut off layer. This is in contrast to traditional microporous materials which have comparable pore sizes on both the upstream and downstream sides of the membrane. The graded nature of asymmetric membranes results in a sidedness to the membrane, requiring knowledge of the upstream side of the membrane for optimal performance.
Our portfolio of asymmetric membrane includes three media types for optimal performance.
Asymmetric Polyethersulfone
The asymmetric polyethersulfone (PES) membranes are constructed specifically for applications that require sterilization of liquids that have high concentrations of particulate. The graded pore structure helps maintain flow rates as the larger-sized particles are captured on the upstream side of the membrane, leaving the smaller pores to carry out the final filtration step.Asymmetric Sub-Micron Polysulfone (BTS)
BTS membranes are made of polysulfone using a patented process exclusive to Pall Corporation resulting in a highly asymmetric (100:1) membrane with pores that gradually decrease in size from the upstream side to the downstream side. The “cut-off” layer of the BTS membrane is only about 10 µm thick, versus conventional membranes with cut off layers of approximately 100-125 µm in thickness. This differential gives the BTS highly asymmetric membrane significantly higher flow with a much lower pressure drop. The BTS asymmetric membrane is well suited for prefiltration, IV filtration, and lysate clearing applications.
Asymmetric Super Micron Polysulfone (MMM)
MMM membranes are super micron filters which have pore sizes ranging from 0.1-20 µm with a 50:1 pore size ratio. Featuring a patented asymmetric pore structure, these media are highly porous and inherently wettable without the use of additional wetting agents. The MMM family of asymmetric membranes are low protein binding and have been certified to comply with United States Pharmacopeia (USP) Biological Reactivity Test, In Vivo <88> for biological safety. Cytotoxicity and hemolysis tests are also performed on the MMM media. This membrane can be gamma and EtO sterilized and is well suited for sample preparation, prefiltration, and blood glucose applications.Asymmetric Polyethersulfone
Typical Membrane Characteristics
| Base Material | Pore Size (µm) | Pore Size Ratio | Thickness (mils) | Thickness (µm) |
|---|---|---|---|---|
| Unsupported polyethersulfone (Supor®)* | 0.2 | 10:1 | 6.9-9.1 | 175.3-231.2 |
| Unsupported polyethersulfone (Supor) | 0.65 | 8:1 | 4.5-6.9 | 114.3-175.3 |
*The Supor name is a registered trademark of Pall Corporation and is not available for use.
Typical Performance Characteristics
Base Material |
Water Bubble Point (psi) |
Water Bubble Point (bar) |
Water Flow (mL/min/cm2 @ 0.7 bar, 10 psi) | Bacterial Retention |
LAL |
|---|---|---|---|---|---|
| Unsupported polyethersulfone (Supor) | 54.3-79.4 | 3.74-5.47 | 27.3-54.0 | 100% retentive when challenged with B. diminuta; (ATCC No. 19146) 107/cm2 @ 30 psi | < 0.25 EU/mL endotoxin utilizing 400 cm2/400 mL LAL reagent water |
| Unsupported polyethersulfone (Supor) | 18.0-38.0 | 124.11-262.0 | 54.0-160.0 | N/A | < 0.25 EU/mL endotoxin utilizing 400 cm2/400 mL LAL reagent water |
Wet time: < 5 seconds
Extractables: < 3.1% in (isopropanol, soxhlet)
Highly Asymmetric Sub-micron Polysulfone (BTS)
Typical Membrane Characteristics
| Base Material | Pore Size (µm) | Pore Size Ratio | Thickness (mils) | Thickness (µm) |
|---|---|---|---|---|
| Unsupported polysulfone (BTS) | 0.05 | 100:1 | 4.1-5.7 | 104.2-144.8 |
| Unsupported polysulfone (BTS) | 0.1 | 100:1 | 4.1-5.7 | 104.2-144.8 |
| Unsupported polysulfone (BTS) | 0.2 | 100:1 | 4.1-5.7 | 104.2-144.8 |
| Unsupported polysulfone (BTS) | 0.3 | 100:1 | 4.1-5.7 | 104.2-144.8 |
| Unsupported polysulfone (BTS) | 0.45 | 100:1 | 4.1-5.7 | 104.2-144.8 |
| Unsupported polysulfone (BTS) | 0.8 | 100:1 | 4.1-5.7 | 104.2-144.8 |
Typical Performance Characteristics
Base Material |
Water Bubble Point (psi) |
Water Bubble Point (bar) |
Water Flow (mL/min/90 mm disc @ 0.7 bar, 10 psi) |
Water Flow (mL/min/47 mm disc @ 0.01 bar, 0.14 psi) |
|---|---|---|---|---|
| Unsupported polysulfone (BTS) | > 80.0 | > 5.52 | 400 | N/A |
| Unsupported polysulfone (BTS) | > 55.0 | > 3.79 | 700 | N/A |
| Unsupported polysulfone (BTS) | > 47.0 | > 3.24 | 1,100 | N/A |
| Unsupported polysulfone (BTS) | > 40.0 | > 2.76 | 1,500 | N/A |
| Unsupported polysulfone (BTS) | > 18.0 | > 1.24 | 2,700 | N/A |
| Unsupported polysulfone (BTS) | N/A | N/A | 6,000 | N/A |
Wet time: < 10 seconds
Asymmetric Super Micron Polysulfone (MMM)
Typical Membrane Characteristics
| Base Material | Pore Size (µm) | Pore Size Ratio | Thickness (mils) | Thickness (µm) |
|---|---|---|---|---|
| Asymmetric super micron polysulfone (MMM) | 0.1 | 50:1 | 4.7-5.7 | 120.0-145.0 |
| Asymmetric super micron polysulfone (MMM) | 0.2 | 50:1 | 4.7-7.3 | 120.0-185.0 |
| Asymmetric super micron polysulfone (MMM) | 0.45 | 50:1 | 4.9-7.3 | 125.0-185.0 |
| Asymmetric super micron polysulfone (MMM) | 0.8 | 50:1 | 6.5-7.9 | 165.0-200.0 |
| Asymmetric super micron polysulfone (MMM) | 5 | 50:1 | 4.7-6.3 | 120.0-160.0 |
| Asymmetric super micron polysulfone (MMM) | 8 | 50:1 | 4.7-6.7 | 120.0-170.0 |
| Asymmetric super micron polysulfone (MMM) | 10 | 50:1 | 4.7-6.7 | 120.0-170.0 |
| Asymmetric super micron polysulfone (MMM) | 20 | 50:1 | 4.5-6.5 | 115.0-165.0 |
Typical Performance Characteristics
| Base Material | Water Bubble Point (psi) |
Water Bubble Point (bar) |
Water Flow (mL/min/90 mm disc @ 0.7 bar, 10 psi) |
Water Flow (mL/min/47 mm disc @ 0.01 bar, 0.14 psi) |
|---|---|---|---|---|
| Asymmetric super micron polysulfone (MMM) | N/A | N/A | 200 | N/A |
| Asymmetric super micron polysulfone (MMM) | N/A | N/A | 350 | N/A |
| Asymmetric super micron polysulfone (MMM) | N/A | N/A | 600 | N/A |
| Asymmetric super micron polysulfone (MMM) | N/A | N/A | 6,000 | N/A |
| Asymmetric super micron polysulfone (MMM) | N/A | N/A | N/A | N/A |
| Asymmetric super micron polysulfone (MMM) | N/A | N/A | N/A | 200 |
| Asymmetric super micron polysulfone (MMM) | N/A | N/A | N/A | 300 |
| Asymmetric super micron polysulfone (MMM) | N/A | N/A | N/A | N/A |
Wet time: < 10 seconds
Applications
- Prefiltration
- Sample clarification
- Clarification of viscous samples
- Particulate removal
- Lysate clearing
Sealing
- Mechanical
- Heat
- Lamination
- Insert molding
- RF welding
Asymmetric Polyethersulfone
| Part Number | Description | Pkg |
|---|---|---|
| S80803 | Supor Asymmetric PES C-200 membrane, 0.2 µm, 8" x 10" sheet | 1/pkg |
| S80800 | Supor Asymmetric PES 650 membrane, 0.65 µm, 8" x 10" sheet | 1/pkg |
Highly Asymmetric Sub-micron Polysulfone 100:1 Pore Size Ratio
| Part Number | Description | Pkg |
|---|---|---|
| T9EXPPA0005S00B | BTS membrane, 0.05 µm, 8" x 10" sheet | 1/pkg |
| T9EXPPA0010S00B | BTS membrane, 0.1 µm, 8" x 10" sheet | 1/pkg |
| T9EXPPA0020S00B | BTS membrane, 0.2 µm, 8" x 10" sheet | 1/pkg |
| T9EXPPA0030S00B | BTS membrane, 0.3 µm, 8" x 10" sheet | 1/pkg |
| T9EXPPA0045S00B | BTS membrane, 0.45 µm, 8" x 10" sheet | 1/pkg |
| T9EXPPA0080S00B | BTS membrane, 0.8 µm, 8" x 10" sheet | 1/pkg |
Asymmetric Super Micron Polysulfone 50:1 Pore Size Ratio
| Part Number | Description | Pkg |
|---|---|---|
| T9EXPPA0010S00M | MMM membrane, 0.1 µm, 8" x 10" sheet | 1/pkg |
| T9EXPPA0020S00M | MMM membrane, 0.2 µm, 8" x 10" sheet | 1/pkg |
| T9EXPPA0045S00M | MMM membrane, 0.45 µm, 8" x 10" sheet | 1/pkg |
| T9EXPPA0080S00M | MMM membrane, 0.8 µm, 8" x 10" sheet | 1/pkg |
| T9EXPPA0500S00M | MMM membrane, 5.0 µm, 8" x 10" sheet | 1/pkg |
| T9EXPPA0800S00M | MMM membrane, 8.0 µm, 8" x 10" sheet | 1/pkg |
| T9EXPPA1000S00M | MMM membrane, 10.0 µm, 8" x 10" sheet | 1/pkg |
| T9EXPPA2000S00M | MMM membrane, 20.0 µm, 8" x 10" sheet | 1/pkg |
