Plasmid Purification and Gene Therapy

Gene therapy is related to vaccines, although the products are mostly intended for therapeutic use, and involves delivering DNA to the target cells in the body, allowing them to produce molecules the lack of which are implicated in genetic disorders, supplement immunity and many other potential treatments.

Production of correctly coded DNA (or RNA) strands for this purpose for use directly in patients, for incorporation into vectors, or into recombinant cells used to produce proteins that are the target product may be challenging, as the DNA molecules are large, strongly charged and often start off in high particulate, viscous solutions.