HDC® II Filter Cartridges for Gas Applications

Pall HDC II all-polypropylene filter cartridges incorporate proprietary HDC II tapered pore polypropylene depth media. The single open-ended (SOE) AB filter cartridge style features a high-area pleated modular element construction designed to fit in sanitary filter housings.

HDC II filter cartridges are well suited for a broad range of fine particle and prefiltration applications where purity, economy and reliability are critical. Typical biopharmaceutical applications include biologicals, pharmaceuticals, fermentation feeds and intermediates, and vaccines.

Features and Benefits

• All-polypropylene construction
• Resin-free, melt-sealed
• Constant density tapered pores
• High-capacity for long-life
• Fixed pore, non-shedding
• Low protein binding
• Low extractables
• Broad chemical compatibilities
• Autoclavable and steamable in situ
• Manufactured for use in conformance with cGMP
• ISO 9000 Certified Quality System
• Pharmaceutical P optimized grades with Certificate of Test provided
• FDA-listed materials per 21 CFR

Note: These filters are also available in Kleenpak Nova capsule format.

Quality and Bio-Safety

Biological Tests

• Meets USP Biological Reactivity Test, in vivo, for Class VI-121 °C Plastics

Effluent Quality Tests*

• Meets Cleanliness per USP Particulates in Injectables
• Non-Fiber-Releasing Non-Pyrogenic per USP
• Bacterial Endotoxins (< 0.25 EU/mL)
• Meets Total Organic Carbon and Water Conductivity per USP Purified Water, pH per USP Sterile Purified Water

* Per lot sample soak or rinse-up flush aliquots.

Operating Limits⁽¹⁾

Operating Temperature	Maximum Differential Pressure
50 °C	5.5 bard (80 psid)
80 °C (Maximum)	4.1 bard (60 psid)

¹ In compatible fluids which do not soften, swell or adversely affect the filter medium or materials of construction Steam Sterilization

 

 

Maximum Cumulative Steam Sterilization

Steam Sterilizing Temperature of AB Steaming Exposure (In situ or Autoclave)

50 hours	Up to 140 °C

 

Retention Ratings

Media Code	Liquid Absolute Rating	Liquid Retention (90%)	Gas Efficiency3 for 0.3 µm Aerosols	Nominal Filter Area4	Gas Flow Rates per 254mm Cartridge2 for Air m3/h, P = 10 mbar (0.15 psi)4
J006	0.6 µm 3	< 1.0 µm 3	100.00 %	0.62 m2 (6.67 ft2)	4
J012	1.2 µm	< 1.0 µm 3	100.00 %	0.69 m2 (7.43 ft2)	10
J025	2.5 µm	< 1.0 µm 3	99.95 %	0.86 m2 (9.26 ft2)	14
J045	4.5 µm	1.2 µm	99.75 %	0.86 m2 (9.26 ft2)	17
J060	6.0 µm	3.0 µm	99 %	0.40 m2 (4.31 ft2)	24
J100	10.0 µm	5.4 µm	93 %	0.52 m2 (5.6 ft2)	39
J200	20.0 µm	10.0 µm	-	0.53 m2 (5.7 ft2)	-
J400	40.0 µm	22.0 µm	-	0.37 m2 (3.98 ft2)	-

² For fluids of 1 cP viscosity. As a general guide for viscosities multiply pressure drop by viscosity in cP. For cartridges of 508, 762 and 1016 mm nominal length, divide differential pressure by 2, 3, and 4 respectively.
³ Based on mineral oil test.
⁴ For 254 mm (10 in.) nominal length cartridge
⁵ Extrapolated value.