What's New

Allegro™ Unison hMSCs
and Media



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Allegro Unison human mesenchymal stem cells (hMSCs) and media facilitate large scale hMSC expansion and accelerate cell therapy and regenerative medicine development. Used along with Pall® SoloHill microcarriers, Allegro biocontainers and the PadReactor® bioreactor system, these hMSC media and cells assist in expansion of up to billions or trillions of hMSCs efficiently and reproducibly without the need for extensive and costly process development.

Kleenpak® Presto Sterile Genderless Connectors



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With its intuitive operation and 3 simple steps – Click, Pull, Twist – the new Kleenpak Presto connector gives even greater levels of sterility assurance. Made from Bisphenol-A free polyethersulfone, each device can be autoclaved or gamma–irradiated. With 100% inspection at point of manufacture, and individual serial numbers that allow device traceability, the Presto connector is available in sizes ¼ in. to ⅝ in. with unique tamper resistant colored coded cap for each size.

Cadence™ BioSMB Process System



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The Cadence™ BioSMB Process system adds to our single-use continuous, multi-column chromatography line with a scalable platform from process development (PD) to clinical manufacture under GMP while maintaining sorbent, buffers, and overall process parameters. The unique design features 8 columns with single-use valves and flow path to deliver flexibility in process with a smaller footprint, and more efficient use of chromatography sorbents.

Pegasus™ Prime Virus Filtration



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Pegasus™ Prime virus removal filters provide robust retention of small viruses to protect critical manufacturing processes, assure drug quality and safeguard health. The gamma irradiated filters and filter capsules combine high flow and robust capacity, to simplify processes and deliver sustainable economy at all scales.

Allegro™ STR 2000 Single-Use Stirred Tank Bioreactor



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Pall continues to improve cell culture with the launch of the 2000 L single-use bioreactor with working volumes of 400 to 2000 L. Pall now has a family of 3 geometrically similar stirred tank bioreactors, all with a direct bottom-driven impellor delivering great power inputs, supporting good, scalable cell culture performance, across the range from 60 L to 2000 L. These systems are the industry’s most compact, ergonomic and intuitive to handle single-use bioreactors, with a height below 3m.

Cadence™ Acoustic Separator



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An innovative, enabling technology for continuous clarification of batch CHO cell culture. Single-use continuous acoustophoretic clarification is optimized for high density CHO cell culture of 20 - 50 x 106 cells/mL and produces a comparable but normalized harvested cell culture fluid to centrifugation, with no cleaning required and improved scalability. An easy-to-use technology without the volume limitations of depth filtration solutions, and avoiding a large footprint or the need for buffer consumption or process additives.

Cadence™ BioSMB PD System



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The first disposable flow path, continuous multi-column chromatography solution to be fully scalable from the process development laboratory to GMP manufacturing scale. Provides the unit operation efficiency of Simulated Moving Bed chromatography, reducing chromatographic media by up to 80% without changing either sorbents or buffers used in the chromatographic process. Use up to 16 columns for increased specific productivity and application flexibility.

HyperCel™ STAR CEX Cation Exchange Chromatography Sorbent



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A catalog item offered in bulk or prepacked columns to improve cation exchange purification at any scale, these new sorbents deliver high dynamic binding capacity at short residence time, and enable the direct capture of protein or impurity removal at moderate conductivity, limiting the dilution. Perfect for high yield, low elution volumes, HyperCel STAR CEX combines with HyperCel STAR AX to form Pall's new ion-exchange chromatography family.

CMM HyperCel™ Cation Exchange Mixed-Mode Chromatography Sorbent



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These new sorbents are a versatile tool, able to efficiently remove HCP and aggregates from mAbs, or to separate very close molecules at any scale. Provided as a catalog item in bulk or prepacked columns, they provide high dynamic binding capacity over repeated cycles and deliver high yields of recovery with low elution volume. With easy regeneration for long service life, these sorbents are ideal for robust, large-scale processing of a variety of fermentation or cell culture feedstocks.