Tangential Flow Filtration Systems

Tangential Flow Filtration Systems

Pre-Designed Systems for Scalable Processing Pall offers scalable, pre-designed systems to suit your specific process needs. Pall Standard systems are ready-to-use, engineered systems with integrated recipe management tools to expedite your approval processes and reduce your time to market.

The pilot system includes the flexibility of both semi and full automation, a UV detector, a pH monitor, an Integrity Analyzer, and an integrated tank. The system expedites the development and scale-up of filtration processes in accordance with FDA cGMP regulations and guidelines.

 Tangential Flow Filtration Systems      

Top: Centramate Pilot Automated Development and Optimization System

Pall Pre-designed Pilot Tangential Flow Filtration Systems

Pall offers a range of pre-designed systems to meet your process goals.
These include:

  • Centramate 0.1 – 0.5 m2 (1 – 5 ft2)
  • Maximate 0.2 – 0.9 m2 (2 – 10 ft2)
  • Centrasette(1) 0.5 – 7.0 m2 (5 – 75 ft2)
  • Centrastak(1) 0.9 – 18.6 m2 (10 – 200 ft2)

    (1) Autotorque hardware included and optional Instrumentation for UV, pH, Conductivity, Integrity, and Auxiliary Pump. Tanks also available.


  • Intuitive Automated Control System
  • Fully scalable design and components
  • Complete validation package with comprehensive IQ/OQ documentation 
  • Compact sanitary ergonomic design for enhanced cleanability, portability, and accessibility
  • Optional AutoTorque™ (AT) hardware provides uniform cassette sealing
  • Comprehensive Recipe Management
  • Adheres to ASME BPE, ANSI ISA, and cGMP standards
  • Time-saving

Process Automation

Puts Control in the Hands of your Process Engineers
User-friendly recipe management tools include a suite of default recipes for pre-production, production, and post-production operations. Your process experts can make applications work without waiting for programmers to sift through cryptic proprietary software code.

The flexible software design enables users to build recipes and develop processes without PLC programming expertise. Our software is ideal for use in a variety of environments, including process:

  • Development
  • Optimization
  • Production

Streamlined Validation

Our recipes are configured from modules which are tested configuration-based sequences that reduce the number of validation steps.


From a touch screen,any authorized user can create and store recipes so an operator can run process tasks simply, easily, and accurately. Pall’s pre-programmed recipes can be used to automatically sanitize, concentrate, recover product, and clean in place.

Data Storage

  • 21 CFR Part 11 compliant data-handling
  • Convenient data storage and retrieval
  • Outputs to electronic or printed formats


  • Real-time trend analysis
  • Historic Trend Overlays
  • Comprehensive Batch Reports
  • Exports common text and table formats

View additional Tangential Flow Filtration Systems and Components.