Prefiltration and Clarification for Proteomics Sample Prep

Although a basic filtration concept, the clarification and prefiltration of samples remains an important function within proteomics. When filtration is used as a prefilter, matching the proper filter media and device to the application is critical. Here, larger pore size filter materials are used to filter solutions prior to more detailed analysis. When selecting the best product for your application, numerous factors need to be considered. Sample viscosity, sample volume and sample recovery are just some of the aspects that will drive the selection of the optimal device. This chart highlights some of our recommended part numbers for proteomics sample prep.

Sample Volume
(dependent on
serum concentration)
Device Sample
< 5 L VacuCap® PF Bottle-top Filter 4628
 < 150 mL Serum Acrodisc® Syringe Filter   4525  
 < 150 mL Acrodisc PSF Syringe Filter     AP-4523
 < 100 mL Acrodisc PF Syringe Filter 4658
 < 1 mL AcroPrep™ 96 Filter Plate   5053
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Proteomics Applications and Protocols

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Acrodisc PF Syringe Filter
Sterile Acrodisc Syringe Filters with Supor Membrane Universal life science membrane with low protein binding.

Acrodisc PSF Syringe Filters
Acrodisc Syringe Filters for General Aqueous and Particulate-laden SamplesAcrodisc syringe filters for general aqueous and particulate-laden samples.

AcroPrep 96-well Filter Plates
AcroPrep 96-well Filter PlatesOptimized for a variety of applications requiring larger per well volume processing.

Serum Acrodisc Syringe Filter
Sterile Acrodisc Syringe Filters with Supor Membrane Superior flow rates and higher throughputs than competitive devices.

VacuCap & VacuCap PF Vacuum Filtration Devices
VacuCap & VacuCap PF Vacuum Filtration Devices Patented small design accepts a variety of collection vessels and reduces storage space and waste.

Literature and Technical Support

See also, information about products for non-critical, coarse filtration.