Tangential Flow Filtration

• Easy to set up and use – Simply connect the TFF device to a pump and pressure gauge(s) with tubing and a few fittings, add your sample to the reservoir and begin filtration.
• Fast and efficient – It is easier to set up and much faster than dialysis. Higher concentrations can be achieved in less time than when using centrifugal devices or stirred cells.
• Perform two steps with one system – Concentrate and diafilter a sample on the same system, saving time and avoiding product loss.
• Can be scaled up or scaled down – Materials of construction and cassette path length allow conditions established during pilot-scale trials to be applied to process-scale applications. TFF devices that can process sample volumes as small as 10 mL or as large as thousands of liters are available.
• Economical – TFF devices and cassettes can be cleaned and reused, or disposed of after single use. A simple integrity test can be performed to confirm that membrane and seals are intact.

Fast, Efficient Biomolecule Processing

Laboratory Scale

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Biopharmaceutical Scale

• Tangential Flow Filtration Home
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