Infusion Filters in Drug Delivery
With the progress in medical treatment, infusion therapy has become increasingly complex, particularly in intensive care units. An increasing number of patients are undergoing complex and intense treatment, during which they encounter critical phases of impaired vital function, frequently accompanied by reduced microcirculation in vital organs.
and Parenteral Nutrition
During intravenous infusion therapy, up to 10 million particles > 2 μm may enter the patient’s blood system every day via infusion solutions.1,2
The Role of Infusion Filters
Infusion filters (pore size rating 0.2 μm) can play a significant role in preventing contamination by integrating them in a point-of-care infusion system to provide effective protection against particles. Several studies have shown that the use of infusion filters considerably reduced complications associated with particles.3, 4
In addition, infusion filters have an integrated hydrophobic membrane which enables them to remove gas bubbles from infusion solutions, significantly minimizing the risk of gas emboli.
Elimination of Oversized Lipid Droplets
Lipid filters (pore size 1.2 μm) safely prevent the infusion of oversized lipid droplets, preventing fat emboli and minimizing particle contamination.
Retention of Bacteria and Bacterial Endotoxins
Infusion filters with positively charged 0.2 μm membranes retain bacteria and their associated endotoxins.