Cord Blood Collection Set

For the collection of up to 150 mL of umbilical cord blood.

Each set contains 25 mL of Citrate Phosphate Dextrose (CPD) anticoagulant.

• Anticoagulant type and volume are specifically selected for cord blood collection to ensure a robust, easy-to-use process:
  • Bag with 200 mL fill volume
  • 25 mL of Citrate Phosphate Dextrose (CPD) anticoagulant
  • Permits the collection of up to 150 mL of cord blood
• Unique collection bag shape maximizes the recovery of cell-rich plasma.
• Dual needles protect against product loss that results from clotting in the needle. This is particularly important when collection is performed at remote sites, often by staff unfamiliar with the procedure.
• Needles contain a finger-friendly contoured hub with a “bevel” up indicator to facilitate a secure needle stick into the umbilical vein.
• Multiple-use sampling port permits sampling for testing and facilitates the addition of solutions such as sedimenting agents.
• In-line spike entry port/tubing is compatible with sterile connection devices. This permits connection to other blood processing components by any preferred means. It also provides a back-up system for sterile connection device failure or lack of availability.
• Pasteurization of product in final packaging reduces the microbial load on exterior of product.

Product No.	791-01, 791-01U
Description	Cord Blood Collection Set
Fill Volume Range	Up to 150 mL cord blood; includes 25 mL CPD anticoagulant
Port Configuration	(2) 16-gauge needles for venipuncture of the umbilical cord; in-line spike; in-line sterile vent; multi-use sampling port
Materials of Construction	Bag: Polyvinyl chloride (PVC) with di (2-ethylhexyl) phthalate (DEHP) plasticizer; Tubing: Ethylene vinyl acetate
Bag Size(s)	20.45 cm length x 8.48 cm width (8.05 in. length x 3.34 in. width)
Sterilization	Steam
Packaging	Individually packaged in foil; 24/box
Shelf Life	3 years
Traceability	Lot number
Regulatory Status	FDA NDA approved; CE marked
Compatible with Other Bags	791-02

Application

For the collection of up to 150 mL of umbilical cord blood. 

Advanced Bag Designs Meet Rigorous Industry Standards

Cord blood stem cells have been effectively used in the treatment of more than 70 malignant and non-malignant diseases, including sickle cell, leukemia, non-Hodgkin’s lymphoma, other forms of cancer, life-threatening anemias, and autoimmune diseases. As a key supplier to the cord blood banking industry, Pall provides a full range of bag sets that are used to prepare the cord blood stem cells for treatment.

Pall’s collection and processing sets are manufactured to cGMP using validated manufacturing processes that ensure safe, consistent and reliable product performance. Each bag is 100% inspected prior to release and is fully traceable by lot number. Pall’s bag sets are uniquely designed to facilitate closed system processing of cord blood stem cells by the volume reduction method developed at the New York Blood Center.¹ Volume reduction maximizes limited storage space while closed system processing minimizes sample loss and reduces the risk of contamination during handling. This method results in a high quality sample available for transplantation. SOP’s referencing Pall bag sets are available at the EMMES website: https://web.emmes.com/study/cord/sop.htm ¹

Assessment of stem cell content and viability after long-term storage is a critical step prior to a successful transplantation. International standards recommend storing a cell sample attached to a unit of cord blood for quality control testing. Pall’s freezing bag includes sufficient tubing for the preparation of segments, enabling a sample aliquot to be cryopreserved with the final product. Using a tube segment for quality control testing prior to transplantation reduces the risk of contamination during the thawing process and provides critical information needed to predict treatment success.

For disease treatments or patient populations that require a higher cell dose to be transplanted, Pall’s advanced freezing bag design divides the sample into two compartments, facilitating transfusion of 80% of the stem cells while retaining 20% of the stem cells for ex vivo cell expansion. Scientific advances in our ability to amplify stem cells will greatly expand the applications for hematopoietic stem cells from cord blood.

Rubinstein, P.; Dobrila, L.; Rosenfield, R.E.; Adamson, J.W.; Migliaccio, G.; Migliaccio, A.R.;Taylor, P.E.; Stevens, C.E. Processing and Cryopreservation of Placental/Umbilical Cord Blood for Unrelated Bone Marrow Reconstitution. Proc Natl Acad Sci USA. 1995, Oct 24;92(22):10119-22.

Facilitate each step in the collection, processing, freezing and transfusion process for cord blood stem cells to ensure a safe, reliable, robust process. See these other Pall products for the processing and cryopreservation of blood and cellular components:

• Transfer/Freezing Bag Set: For processing and freezing 25 mL of cryopreserved, concentrated cord blood stem cells.
• Cell Wash/Infusion Bag Set: For the thaw/washing and subsequent infusion of previously frozen cord blood stem cells.
• Freezing Bag: For the long-term storage of 25 mL of cryopreserved, concentrated blood components.

Product Code	Product Code (Europe)	Description	Packaging
791-01	791-01U	Cord Blood Collection Unit	24 units/case

To Order, Contact:

Pall Medical

Tel: 877.367.7255
Fax: 888.556.7337
pall@rxcrossroads.com

Pall Europe Ltd

Europa House, Havant Street
Portsmouth, PO1 3PD England
Tel: +44 (0)23 9230 3452
Fax: +44 (0)23 9230 3324
Biosvc@Pall.com

Pall Canada

2535 De Miniac
St-Laurent, Quebec H45 1E5
Tel: +1 514.332.7255
Toll-free in Canada: 800.465.8555
Fax: +1 514.332.0996

Pall's cord blood processing products are not available in Asia or Latin America. For cord blood processing products in Asia and Latin America, please contact your local Thermogenesis representative.

Access our complete list of Pall offices worldwide.