Acrodisc Syringe Filters – Critical for Analytical

Reliable Results with Superior Protection


Whether pursuing analytical goals in life science, pharmaceutical methods, research and development, quality control, or environmental applications, Pall’s sample prep Acrodisc® syringe filters offer reliable and reproducible results. Our HPLC, LCMS and IC certified Acrodisc syringe filters efficiently remove particulate contamination from samples, protecting instruments and preventing costly system maintenance and premature column replacement.


Pall’s superior media separation technology ensures:


  • Accurate pore size ratings for better chromatography, and instrument and column protection.
  • Uniform membrane materials (lot-to-lot) for consistent analytical results.
  • Materials of construction selected specifically for analytical analysis with lower extractables and lower API adsorption.


Acrodisc PSF syringe filters are available featuring membranes and pore size configurations to ensure the best compatibility with your sample and application requirements.


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Scientific Poster: Considerations for Proper Syringe Filter Selection


In many laboratories, the need to consistently generate high-quality data means that laboratory managers and technicians must ensure their instruments are performing optimally around the clock. Filtering samples before injection into a chromatography instrument is one of the primary ways that an analyst can protect their column and instrument from unnecessary wear and excess downtime.

Sample filtration performed using syringe filters is an effective and easy method, however, considerations such as retention efficiency and potential extractables must be made.



Download Our New Analytical Syringe Filter Science Briefs:




4 mm Acrodisc Syringe Filters

  • Ideal for small volume sample filtration, ≤ 2 mL
  • Available with PTFE membrane, compatible with harsh organic solvents

13 mm Acrodisc Syringe Filters

  • Ideal sample volume ≤ 10 mL
  • Available with a range of membrane chemistries and pore sizes to ensure the best compatibility with your sample and application requirements
  • Minispike version features a unique small outlet tip allowing for easier handling and a reduced hold-up volume, ≤ 14 μL


25 mm Standard Acrodisc Syringe Filters

  • Broad line of 25 mm syringe filters for HPLC/UHHPLC applications
  • Ideal for sample volumes of ≤ 100 mL
  • Available with a range of membrane chemistries and pore sizes to ensure the best compatibility with your sample and application requirements

25 mm PSF Acrodisc Syringe Filters

  • Features a large effective filtration area for increased sample throughput, ideal for sample volumes of ≤ 125 mL
  • Pall’s proprietary membrane technology and accurate pore size ratings offer superior HPLC column protection, helping extend column life by as much as 52 times
  • Available with a GxF multi-layer prefilter, providing two to four times the throughput of standard prefilter devices
  • Automation certified, designed to be fully compatible and reliable for use with automated robotic handling systems





LCMS and Ion Chromatography Acrodisc Syringe Filters


For LCMS applications Pall supplies the MS Acrodisc syringe filters that are certified with extremely low levels of extractables and feature low ion suppression/enhancement. They are available in both 13 mm and 25 mm formats and contain a water-wettable PTFE membrane with HDPE housing for excellent chemical compatibility that can be used with both organic and aqueous solvents.


Pall’s IC Acrodisc syringe filters have been optimized for ion chromatography sample preparation applications. Available in both 13 mm and 25 mm formats, the syringe filters contain a hydrophilic polyethersulfone (PES) membrane that has undergone several washing steps ensuring the product has low conductivity detectable extractables.