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Monoclonal Antibody (mAbs) Production

End-to-end process support, from development to industrialization

Monoclonal antibodies (mAbs) are the most common type of biological therapeutics. The number of mAbs therapies on the market and under development continues to grow, increasing the need for reliable, scalable manufacturing platforms. 

 

mAb production includes multiple cell culture steps to maximize cell density followed by several downstream unit operations to safely purify the molecule to a high level of purity. While the type and order of these unit operations can vary, there are some fundamental steps required. We have over 30 years of experience in developing and optimizing mAb processes with customers, and a knowledgeable technical team that is ready to partner with you. From process development services and end-to-end platforms, to on-site testing and applications support for specific process steps, we will help you find the best solution based on data and testing.

 

Upstream

     

 

 

Downstream

     




Want to learn more about 

Upstream & Downstream 

process workflows? 

Speak to an expert

 

Upstream

Cell Culture (n-2) / (n-1) / Production

Clarification (Primary / Secondary)

Want to learn more about 

Upstream Process 

workflows? 

Speak to an expert

 

Downstream

Bioburden Filtration

Concentration (Optional)

Virus Inactivation

Anion Exchange (Optional)

Virus Filtration

Concentration and Diafiltration

Bulk Drug Substance Filtration

Want to learn more about 

Downstream Process 

workflows? 

Speak to an expert

 

Complementary Technologies

Connect With An Expert

 

 

 

 

Pall has a global team of over 300 experienced technical professionals to support your molecule from pre-clinical to commercial manufacturing. From process development services and end-to-end platforms, to on-site testing and applications support for specific process steps, we will help you find the best solution based on data and testing.