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June 2020
Scalable Upstream Process Development of Biotherapeutics (APAC)

Biotech | Pall Corporation webinar series

Establishing a platform for developing and manufacturing therapeutic proteins that ensures predictable productivity and product quality will eliminate bottlenecks in tech transfer.

In this case study, Celltheon demonstrates a workflow using the Celltheon SMART Technology Platform in combination with the Allegro™ STR bioreactor range. The time from cDNA to RCB was reduced to less than 4 months while ensuring scalability between 3L to 200L pilot scale, with a pre-defined upstream and  downstream processing platform for monoclonal antibodies and difficult to express proteins.

Participants will learn about:

  • Improvements in current mammalian expression platforms
  • Cell line development and scalability workflows
  • Key features and advantages of using the Allegro STR bioreactors