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Pall Laboratory Filtration Education & Scientific Brief Hub

In the below downloads, our technical scientific laboratory services team and scientists share their experience and research on many aspects of filtration, across a breadth of applications and protocols for life science, microbiology, analytical QC, and environmental testing in our education scientific brief series.

 

Understand filtration fundamentals, such as how to select the right filtration setup or integrity testing, and discovery application specific research and data.  Subscribe to stay up to date as we release new briefs. 

 

1. Understanding Sterile Filtration and Importance of Prefiltration

 
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The importance of sterile filtration and its supporting claims. Learn how prefiltration can actually improve final, sterile filtration speed and efficiency and guidelines to selecting a filtration setup.

 

 

 

 

2. Sterility Filtration: Understanding Integrity Testing

 
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Ensuring the performance of sterility filtration is essential in research and pharmaceutical operations. This scientific brief reviews the two types of integrity tests — destructive and nondestructive — that are commonly used by the industry to validate sterility filter performance.

 

 

 

3. A New, Innovative Process for Clarifying and Sterile Filtering Cells for Protein Purification Workflow

 
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Centrifugation and filtration have been widely accepted as techniques required for clarifying complex cell cultures to recover extracellular proteins such as monoclonal antibodies (mAbs). However, these steps can be time consuming and costly for labs growing their cultures in 24-well plates. In this scientific brief we explore an alternative to the use of centrifugation/filtration/flocculation to clarify and sterilize mammalian cell cultures, through an assessment of a new 24-well clarification and sterile filtration plate format.

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