The Cadence® Single-Use Tangential Flow Filtration (TFF) Modules (P/N: CSUMxxxTxxx) have the fixed membrane area.  The customized SUTFF modules may have more than one cassette installed.  The total membrane area can be calculated by multiplying the membrane area of each cassette by the total number of cassettes installed. 

Forward Flow integrity specification for the Cadence® Single-Use Tangential Flow Filtration (TFF) Modules Modules with T-series Omega™ membrane is ≤ 1600 sccm/m2 (150 sccm/ft2) at 2.0 barg (30 psig) test pressure. The unit sccm means standard cubic centimeters per minute. 

To calculate the maximum allowable air flow rate, multiply the total membrane area in the cassette holder by the Forward Flow integrity specification. 

For example, four Omega OS030T06 cassettes are installed in the customized SUTFF module holder.  The total membrane area is 2.0 m2.  The maximum allowable air flow rate is 3200 sccm or 3200 mL/min.

Airflow rate=(Membrane area)×(Number of cassettes)×(Integrity specification)

Airflow rate=(0.5m^2 )×(4)×(1600 sccm/m^2 )=3200 sccm

Please refer to Pall Publication:

USTR 2896 Instructions For Use - “Cadence™ Single-Use Tangential Flow Filtration (TFF) Modules with Omega™ Membrane”